Endocrine Abstracts

Available evidence suggests that Sclerocarya birrea stem-bark extract (SBE) which possesses hypoglycaemic activity may be useful in the treatment and management of diabetes mellitus. Since diabetes is associated with cardiovascular and kidney complications, we investigated the influence of SBE on blood glucose, blood pressure and renal function in some experimental animal paradigms. For OGTT tests, separate groups (n=6 in each group) of non-diabetic and streptozo...

Previous studies in our laboratories suggest that Hypoxis hemerocallidea corm (African Potato) extract has a potential in the management of diabetes mellitus. Accordingly, we investigated the short-term effect of Hypoxis hemerocallidea corm ethanolic crude extract (APE) on blood glucose levels of Wistar rats (250–300 g b.wt). Oral glucose tolerance tests (OGTT) were conducted in five separate groups (n=6 in each group) of male Wistar rats (250–300 g b...